GLP-1 receptor agonists (such as semaglutide and tirzepatide) have a well-documented list of side effects. Because these medications work by slowing down digestion and mimicking gut hormones that signal fullness to the brain, the vast majority of side effects are gastrointestinal.
May 25, 2026
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Common Side Effects (Mild to Moderate) These are typically most noticeable when first starting the medication or when increasing the dose, and they often improve
